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APJ receptor agonist 8

CAT: 0931-T85710-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T85710-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2049973-39-7
Target
Apelin receptor
Related Pathways
GPCR/G Protein
Purity
0.9983
Bioactivity
APJ receptor agonist 8 is a small molecule agonist of the APJ receptor, enhancing load-independent cardiac contractility in isolated perfused rat hearts. It mimics the action of the endogenous ligand Apelin and has an EC50 of 21.5 μM.
Smiles
N(S([C@H]([C@H](O)C=1N=CC(C)=CN1)C)(=O)=O)C=2N(C(=NN2)C=3N=C(C)C=CC3)C4=C(OC)C=CC=C4OC
Molecular Formula
C24H27N7O5S
Molecular Weight
525.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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