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APJ receptor agonist 5

CAT: 0931-T63153-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63153-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2135514-20-2
Target
Others, Apelin receptor
Related Pathways
Others, GPCR/G Protein
Bioactivity
APJ receptor agonist 5 (compound 3) is a potent and orally active apelin receptor (APJ) agonist (EC 50: 0.4 nM) with excellent pharmacokinetic profiles in rodent heart failure (HF) models and an acceptable safety profile in preclinical toxicology studies, improving cardiac function and useful for HF disease research.
Smiles
C(OCC)C=1N(C(O)=C(C(=O)N2C[C@H](CC2)C3=CC=CC=C3)C(=O)N1)C4=C(OC)C=CC=C4OC
Molecular Formula
C26H29N3O6
Molecular Weight
479.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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