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Anti-inflammatory agent 41

CAT: 0931-T85687-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T85687-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2896204-90-1
Target
Interleukin, NF-κB, TNF
Related Pathways
NF-κB, Immunology/Inflammation, Apoptosis
Bioactivity
The anti-inflammatory agent 41 (13a) markedly inhibits lipopolysaccharide (LPS) -induced expression of the proinflammatory cytokines IL-6 and TNF-α in J774A.1, THP-1, and LX-2 cells, while also preventing the activation of the NF-κB pathway [1].
Smiles
C(NC1=CC=C(OC=2C3=C(C=C(OC)C(OC)=C3)N=CC2)C=C1)(=O)C4=CN(C=5C(C4=O)=CC=CC5)C6=CC=CC=C6
Molecular Formula
C33H25N3O5
Molecular Weight
543.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C