Products for Research Use Only

PolQi2

CAT: 0931-T84770-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T84770-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2565638-16-4
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9919
Bioactivity
PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ. It can be combined with AZD7648 to enhance HDR-mediated integration and editing accuracy.
Smiles
O=C(NC1=NN=C(OCC2=NC=C(Cl)C=C2)S1)C3=CC=NC=C3C=4C=CC=CC4OC
Molecular Formula
C21H16ClN5O3S
Molecular Weight
453.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C