Products for Research Use Only

PolQi1

CAT: 0931-T89335-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T89335-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2607139-80-8
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9897
Bioactivity
PolQi1 is a highly efficient and selective PolΘ (DNA polymerase theta) inhibitor with an IC50 of 2 nM, showing potential for cancer therapy.
Smiles
C(N(C)C1=C(F)C(Cl)=C(F)C=C1)(=O)[C@H]2N(C(=O)NC2)C3=CC(C(F)(F)F)=CC(C)=N3
Molecular Formula
C18H14ClF5N4O2
Molecular Weight
448.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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