Products for Research Use Only

PolQi2

CAT: 0013-GTR19232555-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19232555-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PolQi2 is a small molecule inhibitor of DNA polymerase theta (Polθ) that specifically suppresses its helicase activity. When combined with the DNA-PK inhibitor AZD7648, it enhances homology-directed repair (HDR) efficiency and improves the accuracy of genome editing in cellular models.
CAS Number
2565638-16-4
Field of Research
Cell Biology, Molecular Biology
Purity
99.19% (May vary between batches)
Solubility
DMSO:155 mg/mL (341.48 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.27 mM)
Smiles
O=C (NC1=NN=C (OCC2=NC=C (Cl) C=C2) S1) C3=CC=NC=C3C=4C=CC=CC4OC
Molecular Formula
C21H16ClN5O3S
Molecular Weight
453.9
Storage Conditions
-20°C
Notes
For research use only.