Lu AF27139

• Target :

  P2X Receptor

• Related Pathways :

  Membrane transporter/Ion channel|||Neuroscience

• Purity :

  0.9996

• Bioactivity :

  Lu AF27139 is an effective and selective antagonist of P2X7 receptor (IC50s of 12 and 2.4 nM for human and rat, Kis of 22, 54, and 13 nM for mouse, human, and rat, respectively) . Lu AF27139 can be used in CNS diseases studies.

• Smiles :

  FC(F)(F)c1nc(sc1C(=O)NC[C@@H](N1CCOCC1)c1ccc(Cl)cc1)-c1ncccn1

• Molecular Formula :

  C21H19ClF3N5O2S

• Molecular Weight :

  497.92

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2097117-06-9