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Δ12-Prostaglandin D2

CAT: 0931-T84646-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T84646-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
64072-89-5
Target
Others
Related Pathways
Others
Bioactivity
Prostaglandin D2 (PGD2) is a primary enzymatic prostaglandin derived from PGH2 and is abundantly produced in the cerebrospinal fluid (CSF) by the lipocalin-type PGD synthase, and peripherally by myeloid cells such as mast cells and basophils via a hematopoietic-type PGD synthase. PGD2 is chemically unstable and presents challenges for use and analysis due to its brief in vivo half-life. Δ12-PGD2, an initial decomposition product of PGD2, acts as an intermediate in the pathway to Δ12-PGJ2, a cyclopentenone prostaglandin known for its antimitotic and carcinogenic properties. The metabolism of Δ12-PGD2 involves the addition of thiol nucleophiles, a common pathway for many cyclopentenone prostaglandins.
Smiles
C(/C=C\CCCC(O)=O)[C@@H]1/C(=C\C[C@H](CCCCC)O)/C(=O)C[C@@H]1O
Molecular Formula
C20H32O5
Molecular Weight
352.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
sc-224019AΔ12-Prostaglandin D2
RM-P151472-01Prostaglandin Impurity 12
sc-201257Δ12-PGJ2 (Δ12-Prostaglandin J2)
HY-137219Δ12 (E) -Prostaglandin D2
HY-113505Delta-12-Prostaglandin J2
AR-P33070-01Alprostadil (Prostaglandin E1) Impurity 12
B7010-.115-deoxy-Δ-12,14-Prostaglandin J2
B7010-115-deoxy-?-12,14-Prostaglandin J2
sc-205017A15-deoxy-Δ12,14-Prostaglandin D2
HY-118101-0115-Deoxy-Δ12,14-prostaglandin A1

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