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Prostaglandin D2 methyl ester

CAT: 0931-T36545-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0931-T36545-01Size:500 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
49852-81-5
Target
Prostaglandin Receptor, Others
Related Pathways
GPCR/G Protein, Others, Immunology/Inflammation
Bioactivity
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation. Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2. It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.
Smiles
CCCCC[C@H](O)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(=O)OC)[C@@H](O)CC1=O
Molecular Formula
C21H34O5
Molecular Weight
366.498
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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