(Z) -RG-13022

CAT: 0931-T84525-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T84525-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

149286-90-8

Target

Others, EGFR

Related Pathways

Others, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis

Bioactivity

(Z) -RG-13022 is a tyrosine kinase (TK) inhibitor that preferentially inhibits the TK activity of the EGF receptor, restricting the EGF-stimulated growth of cultured cells. It demonstrates an IC50 of 11 μM for DNA synthesis in HN5 cells, showcasing thrice the potency of its isomer, (E) -RG-13022 (IC50 = 38 μM) . This compound is applied in breast cancer cell research [1] [2].

Smiles

C(=C(\C#N)/C=1C=CC=NC1)\C2=CC(OC)=C(OC)C=C2

Molecular Formula

C16H14N2O2

Molecular Weight

266.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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T28527-01	RG 14893
T16739-01	RG-12525
T12716-01	RG-12915
T28529-01	RG 7152
T34310-01	RG 14921

Alternative Products

Catalog	Name
464659-01	RG-13022
GTR19161212-01	RG 13022
GTR19232816-01	(Z) -RG-13022
A1913-25	RG 108
BA4464-1	RG-12525
HY-P990656-01	RG-6125
HY-171328-01	RG-15
464658-01	RG 7112
327016	RG-6080
sc-507292	RG-7112

(Z) -RG-13022

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