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O-2545 hydrochloride

CAT: 0931-T84516-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T84516-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
874745-43-4
Target
Others, Cannabinoid Receptor
Related Pathways
Others, GPCR/G Protein
Bioactivity
O-2545 is a potent water-soluble central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist with Ki values of 1.5 and 0.32 nM, respectively. Typically, cannabinoid agonists are highly lipophilic and require solubilization through surfactant agents or binding to water miscible substances like albumin, Tween 80, or Emulphor for use. When dissolved in saline, O-2545 has shown high efficacy in mouse behavioral models, administered either intravenously or intracerebroventricularly.
Smiles
OC1=C2[C@]3([C@](C(C)(C)OC2=CC(C(CCCCN4C=CN=C4)(C)C)=C1)(CC=C(C)C3)[H])[H].Cl
Molecular Formula
C26H36N2O2?HCl
Molecular Weight
445
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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