BI-2545

• Target:

  PDE

• Related Pathways:

  Metabolism

• Bioactivity:

  BI-2545 is a potent and selective autotaxin (ATX) inhibitor with IC50 values of 2.2 nM and 3.4 nM for human and rat ATX, respectively, and reduces plasma LPA levels in rats.

• Smiles:

  C (NC (=O) C=1C=C2C (=CC1) N=NN2) [C@@H]3[C@@]4 ([C@]3 (CN (C (OCC5=CC (C (F) (F) F) =CC (C (F) (F) F) =C5) =O) C4) [H]) [H]

• Molecular Formula:

  C23H19F6N5O3

• Molecular Weight:

  527.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2162961-71-7