BI-2545

• Target :

  PDE

• Related Pathways :

  Metabolism

• Bioactivity :

  BI-2545 is a potent and selective autotaxin (ATX) inhibitor with IC50 values of 2.2 nM and 3.4 nM for human and rat ATX, respectively, and reduces plasma LPA levels in rats.

• Smiles :

  C(NC(=O)C=1C=C2C(=CC1)N=NN2)[C@@H]3[C@@]4([C@]3(CN(C(OCC5=CC(C(F)(F)F)=CC(C(F)(F)F)=C5)=O)C4)[H])[H]

• Molecular Formula :

  C23H19F6N5O3

• Molecular Weight :

  527.42

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2162961-71-7