17β-Hydroxywortmannin

CAT:
931-T84510-01
Size:
10 mg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
17β-Hydroxywortmannin - image 1

17β-Hydroxywortmannin

  • Target :

    Others|||PI3K
  • Related Pathways :

    PI3K/Akt/mTOR signaling|||Others
  • Bioactivity :

    17?-Hydroxywortmannin is an orally active phosphatidylinositol-3-kinase (PI-3-kinase) inhibitor, exhibiting an IC50 of 0.5 nM and notably suppresses osteoclast resorption at an IC50 of 10 nM. Additionally, it demonstrates antitumor activity.
  • Smiles :

    C[C@@]12C3=C([C@]4([C@](C)(C[C@H]3OC(C)=O)[C@@H](O)CC4)[H])C(=O)C5=C1C(C(=O)O[C@@H]2COC)=CO5
  • Molecular Formula :

    C23H26O8
  • Molecular Weight :

    430.45
  • Shipping Conditions :

    Cool pack
  • Storage Temperature :

    -20°C
  • CAS Number :

    58053-83-1

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