17β-Hydroxywortmannin

CAT: 0931-T84510-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T84510-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
58053-83-1
Target
Others|||PI3K
Related Pathways
PI3K/Akt/mTOR signaling|||Others
Bioactivity
17?-Hydroxywortmannin is an orally active phosphatidylinositol-3-kinase (PI-3-kinase) inhibitor, exhibiting an IC50 of 0.5 nM and notably suppresses osteoclast resorption at an IC50 of 10 nM. Additionally, it demonstrates antitumor activity.
Smiles
C[C@@]12C3=C([C@]4([C@](C)(C[C@H]3OC(C)=O)[C@@H](O)CC4)[H])C(=O)C5=C1C(C(=O)O[C@@H]2COC)=CO5
Molecular Formula
C23H26O8
Molecular Weight
430.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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