Tafluprost ethyl ester

CAT: 0931-T84470-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T84470-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

209860-89-9

Target

Others, Prostaglandin Receptor

Related Pathways

GPCR/G Protein, Others, Immunology/Inflammation

Bioactivity

Tafluprost, an analog of prostaglandin F2α (PGF2α) that primarily targets the FP receptor, is employed in glaucoma treatment. Tafluprost (free acid) serves as a potent FP receptor agonist with a Ki value of 0.4 nM. Its derivative, tafluprost ethyl ester, potentially offers enhanced lipid solubility relative to its free acid form, possibly leading to superior tissue absorption and reduced effective concentration requirements.

Smiles

CCOC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(F)(F)COc1ccccc1

Molecular Formula

C24H32F2O5

Molecular Weight

438.512

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Tafluprost ethyl ester

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