IMCTA-C14 TFA

• Target :

  Others|||Autophagy|||Antibacterial

• Related Pathways :

  Others|||Microbiology/Virology|||Autophagy

• Bioactivity :

  IMCTA-C14, a detergent and derivative of the microbial metabolite 4-trehalosamine, exhibits a critical micelle concentration (CMC) of 0.11 mM and a hydrophilic-lipophilic balance (HLB) value of 9.72. It effectively extracts proteins, including membrane proteins, from OVK18 ovarian cancer cells at concentrations of 0.05 and 0.5%. Furthermore, IMCTA-C14 demonstrates antibacterial activity against various bacterial strains (MICs = 8-128 µg/ml) and shows cytotoxicity against a spectrum of 52 cancer cell lines (IC50s = 2.9-29.2 µg/ml) . At a concentration of 50 µM, it induces autophagy in OVK18 cells.

• Smiles :

  OC(C(F)(F)F)=O.O[C@@H]([C@@H]([C@H](O1)CO)NCCCCCCCCCCCCCC)[C@@H](O)[C@H]1O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO

• Molecular Formula :

  C26H51NO10.CF3COOH

• Molecular Weight :

  651.71

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C