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IMCTA-C14 TFA

CAT: 0931-T83921-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T83921-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, Autophagy, Antibacterial
Related Pathways
Others, Microbiology/Virology, Autophagy
Bioactivity
IMCTA-C14, a detergent and derivative of the microbial metabolite 4-trehalosamine, exhibits a critical micelle concentration (CMC) of 0.11 mM and a hydrophilic-lipophilic balance (HLB) value of 9.72. It effectively extracts proteins, including membrane proteins, from OVK18 ovarian cancer cells at concentrations of 0.05 and 0.5%. Furthermore, IMCTA-C14 demonstrates antibacterial activity against various bacterial strains (MICs = 8-128 μg/ml) and shows cytotoxicity against a spectrum of 52 cancer cell lines (IC50s = 2.9-29.2 μg/ml) . At a concentration of 50 μM, it induces autophagy in OVK18 cells.
Smiles
OC(C(F)(F)F)=O.O[C@@H]([C@@H]([C@H](O1)CO)NCCCCCCCCCCCCCC)[C@@H](O)[C@H]1O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO
Molecular Formula
C26H51NO10.CF3COOH
Molecular Weight
651.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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