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OP-145 TFA

CAT: 0931-T83849-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T83849-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Bioactivity
OP-145, a derivative of the antimicrobial peptide LL-37, is a synthetic antimicrobial peptide showing activity against E. coli, P. aeruginosa, C. albicans, and A. niger, with minimum inhibitory concentrations (MICs) of 2, 3, 6, and 18 μM, respectively. Utilizing poly (lactic-co-glycolic acid) (PLGA) microspheres loaded with OP-145 effectively prevents biofilm formation in a mouse model of bone infection, which is initiated by surgical femoral fracture and subsequent bacterial inoculation at the fracture site.
Smiles
NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H]1CCCN1C([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@H](CC(C)C)NC([C@H](CCC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@@]([C@H](CC)C)([H])NC([C@H](CCCNC(N)=N)NC([C@H](CCC(O)=O)NC([C@H](C(C)C)NC([C@@]([C@H](CC)C)([H])NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H](CCCCN)NC(CNC([C@@]([C@H](CC)C)([H])NC(C)=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.FC(F)(F)C(O)=O
Molecular Formula
C142H246N46O31.XCF3COOH
Molecular Weight
3093.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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