OP-3633

• Target:

  Others|||Glucocorticoid Receptor

• Related Pathways:

  Endocrinology/Hormones|||Others

• Bioactivity:

  OP-3633 is an effective and selective steroidal glucocorticoid receptor (GR) antagonist (IC50: 29 nM) . OP-3633 shows low progesterone receptor (PR) agonism and androgen receptor (AR) antagonism. It also has an inhibition of GR transcriptional activity.

• Smiles:

  C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@]3(C5=CC=C(N(C)C)C=C5)[H])[C@@](C#CC)(O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]

• Molecular Formula:

  C30H39NO2

• Molecular Weight:

  445.64

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2102494-14-2