ATP-γ-S tetrasodium

CAT: 0931-T83827Size: 2600 μgDry Ice: NoHazardous: No

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CAT#:0931-T83827Size:2600 μg

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CAS Number

88453-52-5

Target

P2Y Receptor, PERK

Related Pathways

Neuroscience, Apoptosis, GPCR/G Protein

Bioactivity

ATP-γ-S tetrasodium (Adenosine-5'-O- (3-thiotriphosphate) tetrasodium) is a purinergic P2Y11 receptor agonist and ATP analog that induces inositol phosphate accumulation, induces insulin secretion from MIN6 pancreatic islet β-cells, and induces an increase in intracellular calcium concentration. ATP-γ-S tetrasodium inhibits the induction of the Junin virus. Junin virus-induced increase in the level of mRNA encoding bone morphogenetic protein 6 (BMP6) reduces particle-forming units (PFUs) in Junin virus-infected primary rat osteoblasts.

Smiles

O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([S-])=O)([O-])=O)([O-])=O)N2C3=NC=NC(N)=C3N=C2.[Na+].[Na+].[Na+].[Na+]

Molecular Formula

C10H12N5Na4O12P3S

Molecular Weight

611.17

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Adenosine-5'-O-(3-thiotriphosphate) (sodium salt)

CAS Number	88453-52-5
PubChem CID	170917373
IUPAC Name	tetrasodium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate
Molecular Formula	C10H12N5Na4O12P3S
Molecular Weight	611.18
Topological Polar Surface Area	305
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	17
Rotatable Bond Count	8
Heavy Atom Count	35
Formal Charge	0
Complexity	788

SMILES

C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N.[Na+].[Na+].[Na+].[Na+]

InChI

InChI=1S/C10H16N5O12P3S.4Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-24-28(18,19)26-29(20,21)27-30(22,23)31;;;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H,20,21)(H2,11,12,13)(H2,22,23,31);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1

InChIKey

PBVFEDMHGRBQSV-KWIZKVQNSA-J

Chemical Structure

2D Structure

CAS: 88453-52-5

CID: 170917373

Formula: C10H12N5Na4O12P3S

MW: 611.18

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	611.18
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	17
Rotatable Bond Count	8
Exact Mass	610.90068013
Monoisotopic Mass	610.90068013
Topological Polar Surface Area	305 Å²
Heavy Atom Count	35
Formal Charge	0
Complexity	788
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	5
Compound Is Canonicalized	Yes

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T211383-01	TNP-ATP tetrasodium
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TSW-01142-01	DdGTPαS tetrasodium
T22496	2-Methylthio-ATP tetrasodium
T84731-01	8-NH2-ATP tetrasodium
TSW-00777-01	2-Amino-ATP tetrasodium
T212148-01	Sp-dGTPαS tetrasodium
T212478-01	Rp-UTP-α-S tetrasodium

Alternative Products

Catalog	Name
GTR19229889	ATP-γ-S tetrasodium
HY-134361	ATP-γ-S (tetrasodium)
HY-137626C	Rp-ATPαS (tetrasodium)
GTR19279962-01	Rp-ATPαS tetrasodium
HY-137626A	Sp-ATPαS (tetrasodium)
HY-137610A	TNP-ATP (tetrasodium)
GTR19263779-01	TNP-ATP tetrasodium
GTR19266934-01	DdATPαS tetrasodium
GTR19266928-01	DdCTPαS tetrasodium
GTR19263875-01	DdTTPαS tetrasodium

ATP-γ-S tetrasodium

Chemical Information

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