Products for Research Use Only
RegisterLogin

ASC-69

CAT: 0931-T82960-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T82960-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1216665-50-7
Target
PD-1/PD-L1
Related Pathways
Apoptosis, Cell Cycle/Checkpoint, Immunology/Inflammation
Bioactivity
ASC-69 (APY69) is a promising potent inhibitor of the PD-1/PD-L1 signaling pathway, classified as a small-molecule compound [1].
Smiles
Cc1cc(Nc2cc([nH]n2)C2CC2)nc(Nc2ccc(CC#N)cc2)n1
Molecular Formula
C19H19N7
Molecular Weight
345.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

2-(4-((4-((5-Cyclopropyl-1H-pyrazol-3-yl)amino)-6-methylpyrimidin-2-yl)amino)phenyl)acetonitrile
CAS Number1216665-50-7
PubChem CID45111335
IUPAC Name2-[4-[[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-methylpyrimidin-2-yl]amino]phenyl]acetonitrile
Molecular FormulaC19H19N7
Molecular Weight345.4
XLogP3.2
Topological Polar Surface Area102
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count26
Formal Charge0
Complexity505
SMILES
CC1=CC(=NC(=N1)NC2=CC=C(C=C2)CC#N)NC3=NNC(=C3)C4CC4
InChI
InChI=1S/C19H19N7/c1-12-10-17(23-18-11-16(25-26-18)14-4-5-14)24-19(21-12)22-15-6-2-13(3-7-15)8-9-20/h2-3,6-7,10-11,14H,4-5,8H2,1H3,(H3,21,22,23,24,25,26)
InChIKey
WMBYJVXSANGBLN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-(4-((4-((5-Cyclopropyl-1H-pyrazol-3-yl)amino)-6-methylpyrimidin-2-yl)amino)phenyl)acetonitrile
CAS: 1216665-50-7
CID: 45111335
Formula: C19H19N7
MW: 345.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight345.4
XLogP33.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass345.17019364
Monoisotopic Mass345.17019364
Topological Polar Surface Area102 Ų
Heavy Atom Count26
Formal Charge0
Complexity505
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T89386-01α-Glucosidase-IN-69
T30123-01ARD-69
T73153-01EGFR-IN-69
T28446-01PQ-69
T205524-01NLRP3-IN-69
T89098-01AChE-IN-69
T62928-01XR8-69
T5399-01GeA-69
T86659-01HSD17B13-IN-69
T69564-01YK-2-69

Alternative Products

CatalogName
HY-W771599-01ASC-69
533286ASC
A3190-10ASC-J9
70R-32211ASC antibody
TRC-A101260-500MGASC 67131
MBS153226-01ASC Peptide
HY-KE7003Asc I
306937-01ASC-1

Popular Products