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Cpm-1285

CAT: 0931-T82672-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T82672-01Size:5 mg
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CAS Number
300349-97-7
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
CPM-1285 induces apoptosis by effectively inhibiting the function of intracellular Bcl-2 and associated death antagonists. It exhibits a high binding affinity for Bcl-2, with an IC50 of 130 nM, and has been demonstrated to decrease tumor burden in mice [1].
Smiles
C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCCCCC)=O)CCCCN)=O)CC(N)=O)=O)CC(C)C)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(NCC(N[C@@H](CC(C)C)C(O)=O)=O)=O)CCCCN)=O)=O)CO)=O)=O)CCC(O)=O)=O)=O)CCC(O)=O)=O)CC(O)=O)=O)CO)=O)CCSC)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCC(O)=O)=O)CCCNC(=N)N)=O)=O)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)C)=O)C)=O)C=4C=5C(NC4)=CC=CC5
Molecular Formula
C153H240N44O42S
Molecular Weight
3399.88
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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