CU06-1004

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  CU06-1004 (Sac-1004) is an orally active compound that mitigates endothelial dysfunction by inhibiting hyperpermeability and inflammation. It reduces vascular leakage and inflammation in multiple animal models, including diabetic retinopathy, stroke, cancer, and inflammatory bowel disease. CU06-1004 also improves conditions in a CDAA-induced mouse model of NASH and enhances cardiac function [1] [2] [3].

• Smiles:

  C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](OC5O[C@H](COC(C)=O)[C@@H](OC(C)=O)C=C5)CC4)(CC1)[H])[H])(CC[C@@H]2\C(=C\CCCC(OC)=O)\C)[H]

• Molecular Formula:

  C37H54O8

• Molecular Weight:

  626.82

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1296734-08-1