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Cyclorasin 9A5

CAT: 0931-T82637-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T82637-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1782098-79-6
Target
Raf|||Ras
Related Pathways
GPCR/G Protein|||MAPK
Bioactivity
Cyclorasin 9A5 is a cell-permeable, 11-residue cyclic peptide that orthosterically disrupts the Ras-Raf protein interaction, demonstrating an inhibition concentration (IC50) of 120 nM [1].
Smiles
C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CCCC)NC(=O)[C@H](CC4=CC=C(F)C=C4)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC5=CC6=C(C=C5)C=CC=C6)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)NC(=O)[C@]([C@@H](C)O)(NC3=O)[H]
Molecular Formula
C75H108FN25O13
Molecular Weight
1586.82
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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