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Cyclotraxin B TFA

CAT: 0931-T75832-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T75832-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
Cyclotraxin B TFA, a cyclic peptide, is a highly potent and selective non-competitive inhibitor of TrkB, effectively impeding BDNF-triggered TrkB activity without altering BDNF binding affinity, with an IC50 of 0.30 nM. It crosses the blood-brain barrier, demonstrating analgesic and anxiolytic-like behavioral effects [1] [2] [3].
Molecular Formula
C50H74F3N13O19S3
Molecular Weight
1314.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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