DA-PROTAC

• Target :

  PROTACs|||Ligand for E3 Ligase

• Related Pathways :

  PROTAC

• Bioactivity :

  DA-PROTAC is a potent degrader of the copper ion-transport proteins Atox1 and CCS, capable of binding to both proteins and facilitating their association with E3 ligase. This interaction enhances the ubiquitination and subsequent proteasomal degradation of Atox1 and CCS. DA-PROTAC is utilized in triple negative breast cancer research [1].

• Smiles :

  N(C(COCCCOCC(NC(C(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1)C(C)(C)C)=O)=O)C=4C5=C(SC4C(NC6=C(Br)C=C(F)C=C6F)=O)N=C7C(=C5)CCC7

• Molecular Formula :

  C46H50BrF2N7O8S2

• Molecular Weight :

  1010.96

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2488660-12-2