GPR139 agonist-2

CAT: 0931-MF-0159458-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0159458-01Size:5 mg
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AVAILABILITY: InStock
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CAS Number
2983118-29-0
Target
Others|||GPCR
Related Pathways
Endocrinology/Hormones|||Others|||GPCR/G Protein
Bioactivity
GPR139 agonist-2 (compound 20a), a potent GPR139 agonist with an EC50 of 24.7 nM, has demonstrated efficacy in rescuing social interaction deficits and alleviating cognitive deficits in murine schizophrenia models, indicating its potential in antischizophrenia drug research [1].
Smiles
O=C1N2C(C=NN1CC(N[C@@H](C)C3=CC=C(OC(F)(F)F)C=C3)=O)=CC=C2
Molecular Formula
C17H15F3N4O3
Molecular Weight
380.32
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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