ICMT-IN-21

• Target:

  Others|||Transferase

• Related Pathways:

  Metabolism|||Others

• Bioactivity:

  ICMT-IN-21 (compound 6ag) is an ICMT inhibitor with an IC50 of 8.8 µM, featuring sulfonamide-modified farnesyl cysteine (SMFC) . Its farnesyl and carboxylic acid motifs are critical for ICMT inhibition [1].

• Smiles:

  S(N[C@@H](CSC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)C(O)=O)(=O)(=O)C1=CC=CS1

• Molecular Formula:

  C22H33NO4S3

• Molecular Weight:

  471.7

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1310740-69-2