RIPK3-IN-4

• Target:

  RIP kinase

• Related Pathways:

  Apoptosis|||NF-?B

• Bioactivity:

  RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor that mitigates necroptosis, inflammatory responses, and HK-2 cell damage. It alleviates acute kidney injury by attenuating Cisplatin- and I/R-induced kidney damage, along with associated inflammatory responses and necroptosis [1].

• Smiles:

  O=C(NC=1C=CC=C(Br)C1)NC2=CC(OC=3C=CC=4N=C(SC4C3)NC(=O)C5CC5)=CC=C2F

• Molecular Formula:

  C24H18BrFN4O3S

• Molecular Weight:

  541.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2304617-58-9