RIPK3-IN-3
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RIPK3-IN-3
Target :
Others|||MLK|||RIP kinaseRelated Pathways :
Apoptosis|||NF-?B|||Others|||MAPKBioactivity :
RIPK3-IN-3 (compound 20) is a selective RIPK3 inhibitor with a potent IC50 value of 10 nM, effectively blocking RIPK3-mediated phosphorylation of MLKL, preventing oligomerization and necroptosis induction. Moreover, RIPK3-IN-3 suppresses CXCL5 secretion and impedes AsPC-1 cell migration and invasion [1].Molecular Formula :
C16H11N5SMolecular Weight :
305.36Shipping Conditions :
Cool packStorage Temperature :
-20°C
