RMC-7977

• Target:

  ERK|||Ras|||AMPK|||Raf|||Apoptosis|||PARP|||Kras|||S6 Kinase

• Related Pathways:

  DNA Damage/DNA Repair|||MAPK|||GPCR/G Protein|||PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic|||Apoptosis

• Purity:

  0.9991

• Bioactivity:

  RMC-7977 is a highly selective inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS with anticancer activity for the study of solid tumors with KRAS G12C mutations.

• Smiles:

  O=C1OCC(C)(C)CC=2C3=CC(=CC=C3N(C2C=4C=C(C=NC4C(OC)C)N5CCN(CC5)C6CC6)CC)C=7N=C(SC7)CC(NC(=O)C8C9COCC89)C(=O)N%10NC1CCC%10

• Molecular Formula:

  C47H60N8O6S

• Molecular Weight:

  865.09

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2765082-12-8