RMC-113

• Target:

  DNA/RNA Synthesis|||PI3K|||SARS-CoV|||Autophagy

• Related Pathways:

  Cell Cycle/Checkpoint|||Microbiology/Virology|||PI3K/Akt/mTOR signaling|||Autophagy|||DNA Damage/DNA Repair

• Bioactivity:

  RMC-113 is an inhibitor of PIP4K2C and PIKfyve, with Ki values of 46 nM and 370 nM, respectively. It reverses autophagy flux impairment induced by SARS-CoV-2 and exhibits antiviral activity.

• Smiles:

  C(#CC=1SN=C2C=C(C=NC12)C=3C=CC(OC)=C(OC)C3)C=4C=NC=CC4

• Molecular Formula:

  C21H15N3O2S

• Molecular Weight:

  373.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2258606-34-5