AKE-72

• Target:

  Bcr-Abl

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Angiogenesis|||Cytoskeletal Signaling

• Purity:

  0.983

• Bioactivity:

  AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.

• Smiles:

  O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCN(CC)CC2)C=3C=CC=C(C#CC4=CC=CC=5NN=C(N)C45)C3

• Molecular Formula:

  C30H29F3N6O

• Molecular Weight:

  546.59

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2566525-18-4