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NLRP3-IN-72

CAT: 0931-T205657-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205657-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3043952-13-9
Target
NOD-like Receptor (NLR), Pyroptosis, Interleukin, ROS
Related Pathways
Apoptosis, Immunology/Inflammation
Bioactivity
NLRP3-IN-72 (Compound 2) is a benzimidazole derivative. It exhibits anti-inflammatory and antioxidant properties, with an IC50 of 0.3 μM for NLRP3 IL-1β, a PD50 of 0.4 μM for protection against cell pyroptosis, and an EC50 of 0.6 μM for inducing HO-1.
Smiles
FC=1C=CC2=C(N=C(NC3=NC=4C=C(C=CC4O3)CN(C)CC)N2C)C1
Molecular Formula
C19H20FN5O
Molecular Weight
353.393
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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