MSIRK

• Target:

  ERK

• Related Pathways:

  MAPK

• Purity:

  0.9926

• Bioactivity:

  MSIRK (G-Protein ?? Binding Peptide) is a cell-permeable activator of ERK 1/2 with an EC50 of 2.5-5 ?M. It disrupts the interaction between the ? and ?? subunits, facilitating ? subunit dissociation without inducing nucleotide exchange [1].

• Smiles:

  C([C@H](CC1=CC=C(O)C=C1)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCCCCCCCCC)=O)CO)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCCN)=O)C)=O)CC(C)C)=O)CC(N)=O)=O)[C@H](CC)C)=O)CC(C)C)=O)=O)(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)CC(O)=O)=O)CCC2

• Molecular Formula:

  C93H150N20O25

• Molecular Weight:

  1948.31

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  593267-11-9