MSIRK

CAT: 0804-HY-P5985-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P5985-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
MSIRK (G-Protein βγ Binding Peptide) is an cell-permeable activator of ERK1/2, with EC50 of 2.5-5 μM. mSIRK disrupts the interaction between α and βγ subunits and promotes α subunit dissociation without stimulating nucleotide exchange[1].
CAS Number
[593267-11-9]
UNSPSC
12352209
Target
ERK
Type
Peptides
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/msirk.html
Purity
99.33
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(C=C1)=CC=C1C[C@H](NC(CNC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H]([C@@H](C)CC)NC([C@H](CO)NC(CCCCCCCCCCCCC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(N2[C@@H](CCC2)C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@H](C(O)=O)CC(O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O
Molecular Formula
C93H150N20O25
Molecular Weight
1948.31
References & Citations
[1]Farida Goubaeva, et al. Stimulation of Cellular Signaling and G Protein Subunit Dissociation by G Protein βγ Subunit-binding Peptides. J Biol Chem. 2003 May 30;278 (22) :19634-41.|[2]Zhang XL, et al. Y27632 induces tongue squamous cell carcinoma cell apoptosis through MAPK-ERK/JNK signal. De Gruyter Brill.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

Alternative Products

CatalogName
MF-0099810-01MSIRK
A24107-5MSIRK 5mg
MF-0127040-01MSIRK (L9A)
A24107-10MSIRK 10mg
A24107-50MSIRK 50mg
A24107-100MSIRK 100mg

Popular Products