MSIRK (L9A)

• Description:

  MSIRK (L9A) is a cell-permeable, N-myristoylated G-Protein Binding Peptide (mSIRK) . mSIRK (L9A) contains a single point mutation (Leu9 to Ala) . mSIRK (L9A) cannot enhance ERK1/2 phosphorylation. mSIRK (L9A) can be used as a control peptide[1].

• UNSPSC:

  12352209

• Target:

  ERK

• Type:

  Peptides

• Related Pathways:

  MAPK/ERK Pathway; Stem Cell/Wnt

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/msirk-l9a.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@H](CO)NC(CCCCCCCCCCCCC)=O)N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(NCC(N[C@@H](CC1=CC=C(C=C1)O)C(N2[C@@H](CCC2)C(N[C@@H](CC(O)=O)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula:

  C90H144N20O25

• Molecular Weight:

  1906.23

• References & Citations:

  [1]Goubaeva F, et al. Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides. J Biol Chem. 2003 May 30;278 (22) :19634-41.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported