MSIRK (L9A)

• Description:

  MSIRK (L9A) is a cell-permeable, N-myristoylated G-Protein Binding Peptide (mSIRK) . mSIRK (L9A) contains a single point mutation (Leu9 to Ala) . mSIRK (L9A) cannot enhance ERK1/2 phosphorylation. mSIRK (L9A) can be used as a control peptide[1].

• UNSPSC:

  12352209

• Target:

  ERK

• Type:

  Peptides

• Related Pathways:

  MAPK/ERK Pathway; Stem Cell/Wnt

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/msirk-l9a.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C ([C@H] (CO) NC (CCCCCCCCCCCCC) =O) N[C@@H] ([C@@H] (C) CC) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (CCCCN) C (N[C@@H] (C) C (N[C@@H] (CC (C) C) C (N[C@@H] (CC (N) =O) C (N[C@@H] ([C@@H] (C) CC) C (N[C@@H] (C) C (NCC (N[C@@H] (CC1=CC=C (C=C1) O) C (N2[C@@H] (CCC2) C (N[C@@H] (CC (O) =O) C (N[C@@H] (CC3=CC=C (C=C3) O) C (N[C@@H] (CC (O) =O) C (O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O

• Molecular Formula:

  C90H144N20O25

• Molecular Weight:

  1906.23

• References & Citations:

  [1]Goubaeva F, et al. Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides. J Biol Chem. 2003 May 30;278 (22) :19634-41.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported