BMAP-18

• Target :

  Antibacterial

• Related Pathways :

  Microbiology/Virology

• Bioactivity :

  BMAP-18 is a biologically active peptide, a truncated derivative of BMAP-27, which is part of the Cathelicidin family of peptides known for their potent bactericidal properties against pathogens such as Staphylococcus aureus, Streptococcus uberis, and Escherichia coli. Unlike the full-length BMAP-27, which can be cytotoxic to human erythrocytes and neutrophils at concentrations higher than required for its antimicrobial effect, BMAP-18 offers increased cell selectivity due to its reduced hemolytic activity while maintaining effective antimicrobial function.

• Smiles :

  [C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@H](CCCNC(=N)N)NC(CN)=O)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O

• Molecular Formula :

  C113H188N34O20

• Molecular Weight :

  2342.92

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1245798-31-5