Phrixotoxin-1

• Target:

  Potassium Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Bioactivity:

  Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels, originates from the venom of the theraphosid spider Phrixotrichus auratus [1] [2].

• Smiles:

  C ([C@H] (NC ([C@@H] (NC ([C@H] (CC=1C=2C (NC1) =CC=CC2) NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CC3=CC=C (O) C=C3) N) =O) CS) =O) CCC (N) =O) =O) CCCCN) =O) =O) CCSC) =O) C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (NCC (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@@H] (CC=4C=5C (NC4) =CC=CC5) C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@@H] ([C@H] (CC) C) C (N) =O) =O) [C@H] (CC) C) =O) CCCCN) =O) CCCCN) =O) CS) =O) =O) CC (C) C) =O) CCCNC (=N) N) =O) CS) =O) [C@@H] (C) C) =O) CC (C) C) =O) =O) CCC (O) =O) =O) CS) =O) CS) =O) CCCCN) =O) CCCNC (=N) N) =O) C) =O) CO) =O) CC (O) =O) =O) CS) =O) [C@@H] (C) O) =O) C=6C=7C (NC6) =CC=CC7

• Molecular Formula:

  C156H246N44O37S7

• Molecular Weight:

  3554.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  221872-97-5