TNG-462

• Target :

  Histone Methyltransferase

• Related Pathways :

  Chromatin/Epigenetic

• Purity :

  0.987

• Bioactivity :

  TNG-462 is a potent and selective PRMT5 inhibitor with antitumor activity and oral activity, primarily for the treatment of methylthioadenosine phosphorylase (MTAP) -deficient and/or methylthioadenosine (MTA) -accumulating cancers (e.g., non-small-cell lung cancer, pancreatic cancer, bladder cancer, and hematologic malignancies) .

• Smiles :

  C(C(NC=1C=C(CC)C(N)=NC1)=O)(=O)N2[C@H](CC[C@H](C)C2)C=3C=C4C(=CC3)SC(=N4)C5CCN(C)CC5

• Molecular Formula :

  C28H36N6O2S

• Molecular Weight :

  520.69

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2760483-96-1