αvβ1 integrin-IN-2

• Target:

  Integrin

• Related Pathways:

  Cytoskeletal Signaling

• Bioactivity:

  ?v?1 integrin-IN-2 (compound 32) is a potent inhibitor of ???1 and ?5?1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. This compound also inhibits other integrins with IC50 values of 380 nM (???3), 280 nM (???5), 230 nM (???6), and 87 nM (???8), as determined by the SPRA assay [1].

• Smiles:

  C(CC=1C=C(OCCC=2NC=3C(=CC2)CCCN3)N(C)N1)(CC(O)=O)C4=C(OC)C=CC(C(C)(C)C)=C4

• Molecular Formula:

  C29H38N4O4

• Molecular Weight:

  506.64

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2234874-68-9