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αvβ1 integrin-IN-2

CAT: 0931-T79792-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79792-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2234874-68-9
Target
Integrin
Related Pathways
Cytoskeletal Signaling
Bioactivity
αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. This compound also inhibits other integrins with IC50 values of 380 nM (ανβ3), 280 nM (ανβ5), 230 nM (ανβ6), and 87 nM (ανβ8), as determined by the SPRA assay [1].
Smiles
C(CC=1C=C(OCCC=2NC=3C(=CC2)CCCN3)N(C)N1)(CC(O)=O)C4=C(OC)C=CC(C(C)(C)C)=C4
Molecular Formula
C29H38N4O4
Molecular Weight
506.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C