αMβ2 integrin agonist-1

CAT: 0931-T212302-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T212302-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Integrin

Related Pathways

Cytoskeletal Signaling

Bioactivity

αMβ2integrinagonist-1 (Compound 8) is a highly selective αMβ2 integrin agonist with anti-inflammatory properties (EC50=1.4 nM) . It activates integrin-mediated cell adhesion and the JNK/ERK signaling pathway. Additionally, αMβ2integrinagonist-1 induces polarization of tumor-associated macrophages and enhances antitumor T-cell immune responses. This compound holds potential for research in cancer and chronic inflammatory diseases such as pancreatic cancer and rheumatoid arthritis.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
GTR19265046-01	αMβ2 integrin agonist-1
GTR19264664-01	α5β1 integrin agonist-2
sc-43126-PR	Integrin α1 (m) -PR
sc-65429	Integrin αM (LM2/1)
sc-35675-PR	Integrin β1 (m) -PR
sc-35675	Integrin β1 siRNA (m)
sc-43126	Integrin α1 siRNA (m)
sc-65429 PE	Integrin αM (LM2/1) PE
sc-35675-SH	Integrin β1 shRNA Plasmid (m)
sc-430957-HDR	Integrin α1 HDR Plasmid (m)

αMβ2 integrin agonist-1

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