EGFR-IN-89

CAT: 0931-T79775-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T79775-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2413029-40-8

Target

EGFR

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

Bioactivity

EGFR-IN-89 (compound 13k) is a fourth-generation inhibitor that selectively targets EGFR mutations, showing potent activity with an IC50 of 10.1 nM against Del19/T790M/C797S mutations, and demonstrating greater selectivity for mutant forms over wild type [1].

Smiles

N(C1=C2C(=NC(NC3=CC(F)=C(C=C3)N4CCN(CC)CC4)=N1)NC=C2)C5=C(N(S(C)(=O)=O)C)C=CC=C5

Molecular Formula

C26H31FN8O2S

Molecular Weight

538.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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MBS5821436	EGFR-IN-89
MBS131532	H 89 (Protein kinase inhibitor H-89; H89; H 89)
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MBS5772662	TG-89
GTR19176686-01	M‐89
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MBS3843288-01	M-89
P36738	PJL 89
GTR19292516-01	SCOTfluor-89

EGFR-IN-89

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