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Caspase-3 activator 1

CAT: 0931-T79743-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T79743-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Pyroptosis
Related Pathways
Apoptosis, Immunology/Inflammation
Bioactivity
Caspase-3 activator 1 (compound 4b), a Ru (III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage, enabling Caspase-3 to process gasdermin E (GSDME), resulting in GSDME-N terminus production and perforation of the gastric tumor cell membrane. Furthermore, compound 4b induces pyroptosis and subsequent immune responses and can be incorporated with decitabine (DCT) into the 4b-DCT-Lip lipid delivery system [1].
Molecular Formula
C28H27N6O2RuS2
Molecular Weight
644.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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