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DHFR-IN-8

CAT: 0931-T79734-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79734-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, DHFR, Antibacterial
Related Pathways
Metabolism, Microbiology/Virology, Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair
Bioactivity
DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth. This compound effectively suppresses methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 with an IC50 of 15.6 ng/mL in mouse models of systemic and thigh infections [1].
Molecular Formula
C18H14N6S
Molecular Weight
346.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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HY-156122DHFR-IN-8
sc-74594DHFR (F-8)
ant-596DHFR
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10R-3832DHFR antibody
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