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RET-IN-25

CAT: 0931-T79726-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79726-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2965703-02-8
Target
C-RET, Others
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors, Others
Bioactivity
RET-IN-25 (compound 6b) is an anticancer RET kinase inhibitor effective against medullary thyroid carcinoma (MTC), with half-maximal inhibitory concentrations (IC50s) of 3.6 μM at 3 days and 3.0 μM at 6 days in TT (C634R) MTC [1].
Smiles
O=[N+](C1=CC=C(N=C2)C(C3=C2C(NC(C4=CC=C(C=C4)C)=O)=C(C(OCC)=O)S3)=C1)[O-]
Molecular Formula
C22H17N3O5S
Molecular Weight
435.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C