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Lepadin H

CAT: 0931-T79639-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T79639-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
412328-25-7
Target
Ferroptosis
Related Pathways
Apoptosis
Bioactivity
Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing lipid peroxidation. It simultaneously decreases SLC7A11 and GPX4 levels while upregulating ACSL4 expression, thereby inducing ferroptosis via the p53-SLC7A11-GPX4 pathway [1].
Smiles
C(CCC[C@@H](CCC)O)[C@@H]1[C@]2([C@](N[C@@H](C)[C@H](OC(/C=C/C=C/CCC)=O)C2)(CCC1)[H])[H]
Molecular Formula
C26H45NO3
Molecular Weight
419.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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