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LYP-IN-3

CAT: 0931-T79634-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79634-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Phosphatase
Related Pathways
Metabolism
Bioactivity
LYP-IN-3 (compound D34) is a selective Lymphoid-tyrosine phosphatase (LYP) inhibitor (Ki=0.93 μM) that modulates the T-cell receptor (TCR) signaling pathway during tumor progression. It promotes T-cell activation, hinders M2 macrophage polarization, and increases PD-1/PD-L1 expression. When combined with PD-1/PD-L1 inhibitors, LYP-IN-3 may enhance cancer immunotherapy [1].
Molecular Formula
C35H27NO6S
Molecular Weight
589.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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