AChE/A?-IN-2AChE/A?-IN-2 - High-quality laboratory reagent available from Gentaur. Catalog: 931-T79571-01.931-T79571-01931-T79571-01Business & Industrial > Science & LaboratoryAChE/A?-IN-2
Gentaur
EUR12027-02-21

AChE/A?-IN-2

CAT:
931-T79571-01
Size:
5 mg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
AChE/A?-IN-2 - image 1

AChE/A?-IN-2

  • Target:

    Others|||Cholinesterase (ChE) |||Beta Amyloid|||iGluR
  • Related Pathways:

    Neuroscience|||Others|||Membrane transporter/Ion channel
  • Bioactivity:

    AChE/A?-IN-2 (compound 33) is a potent, orally active acetylcholinesterase (AChE) inhibitor (IC50: 135 nM), an NMDA receptor antagonist (GluN1-1b/GluN2B subunit combination, IC50: 5.054 ?M), inhibits A? aggregation, demonstrates favorable blood-brain barrier permeability, and enhances cognitive and spatial memory in a rat model [1].
  • Molecular Formula:

    C20H25ClN4
  • Molecular Weight:

    356.89
  • Shipping Conditions:

    Cool pack
  • Storage Temperature:

    -20°C