ROR? antagonist 1

CAT: 0931-MF-0157256-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0157256-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ROR
Related Pathways
Metabolism
Bioactivity
ROR? antagonist 1 (compound 22), a potent derivative of betulinic acid, acts as an antagonist to ROR? with a dissociation constant (K D) of 0.18 ?M. It demonstrates anti-proliferative effects in the HPAF-II pancreatic cancer xenograft model, inhibits the RAS/MAPK and AKT/mTORC1 signaling pathways, and triggers caspase-dependent apoptosis in pancreatic cancer cells [1].
Molecular Formula
C35H60N2O2
Molecular Weight
540.86
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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