Products for Research Use Only
RegisterLogin

INF200

CAT: 0931-T79446-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T79446-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Pyroptosis, NOD-like Receptor (NLR)
Related Pathways
Apoptosis, Immunology/Inflammation
Bioactivity
INF200 (compound 5), a sulfonylurea-based inhibitor of NLRP3 and associated pyroptosis, exhibits cardiometabolic benefits in a rat model of high-fat diet (HFD) -induced metaflammation and demonstrates anti-inflammatory effects by reducing IL-1β release in human macrophages at a concentration of 10 μM. Additionally, it enhances glucose and lipid profiles, diminishes systemic inflammation and cardiac dysfunction biomarkers, notably BNP, and ameliorates myocardial damage linked to ischemia/reperfusion injury (IRI) as assessed by hemodynamic parameters [1].
Molecular Formula
C13H13ClN2O4
Molecular Weight
296.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5821108INF200

Popular Products