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PROTAC α-synuclein degrader 5

CAT: 0931-T79250Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79250Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2781922-42-5
Target
PROTACs
Related Pathways
PROTAC
Bioactivity
PROTAC α-synuclein degrader 5 is a highly selective (PROTAC) compound targeting and degrading α-synuclein aggregates, with a DC50 value of 7.51 μM and a maximum degradation rate (Dmax) of 89%. It incorporates the probe molecule sery308 and E3 ligase ligands, suitable for neurological disease research [1].
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOCCOCCNC(CNC4=CC(=CC=C4)C=5C=C(NN5)C=6C=C7C(=CC6)OCO7)=O
Molecular Formula
C39H41N7O10
Molecular Weight
767.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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